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The American Psychiatric Association Publishing Textbook of Neuropsychiatry and Clinical Neurosciences, Sixth Edition

Edited by David B. Arciniegas, M.D., Stuart C. Yudofsky, M.D., and Robert E. Hales, M.D., M.B.A.

  • ISBN 978-1-61537-187-7
  • Item #37187

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For more than three decades, the Textbook of Neuropsychiatry and Clinical Neurosciences has been the gold standard for understanding the structural and functional foundations and rapidly evolving knowledge base of neuropsychiatric disorders. In the new edition, the esteemed editors have undertaken a complete reorganization, reconceptualizing the way the material is presented and integrating considerations of neuropsychiatric symptoms, syndromes, and treatments into chapters addressing the neuropsychiatry of neurodevelopmental disorders, acquired neurological conditions, neurodegenerative disorders, and primary psychiatric disorders. The result is a text that flows easily and logically from general principles to specific diagnostic tools and conditions, making it a clinically relevant and eminently practical guide for medical students and residents, psychiatrists, neurologists, psychologists and neuropsychologists, as well as a broad range of professionals who work in diverse clinical settings (e.g., the general hospital setting, physical medicine/rehabilitation hospitals, psychiatric institutes, community mental health centers, alcohol and chemical dependency programs, and outpatient services and doctors' offices).
The book possesses a multitude of useful attributes and features:

  • The new edition is thoroughly compatible with the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders.
  • The chapters are complete unto themselves, allowing for easy retrieval and use by clinicians facing daily challenges in the field. Extensive references allow for further research and study in quieter moments.
  • Chapters on specific disorders have consistent structures, where appropriate. For example, the chapter on Autism Spectrum Disorders has sections on background, prevalence, etiology, neurobiology, clinical presentation, assessment, differential diagnosis, comorbidity, research, interventions and treatment, and medication.
  • The prestigious roster of contributors boasts both luminaries and emerging leaders in behavioral neurology and neuropsychiatry, providing readers with diverse perspectives.
  • The material is supported by scores of tables, graphs, and illustrations, including PET, CT, and MRI images.

Neuropsychiatry has come a long way from the days when patients with neuropsychiatric conditions routinely fell through the cracks of the healthcare system. The Textbook of Neuropsychiatry and Clinical Neurosciences provides comprehensive, current, and evidence-based coverage in a forward-looking volume to train a new generation of clinicians in this important work.


  • Preface
  • Chapter 1. Neurobiological Bases of Behavior
  • Chapter 2. Neuropsychiatric Assessment
  • Chapter 3. Neuropsychological Assessment
  • Chapter 4. Neuroimaging in Neuropsychiatry
  • Chapter 5. Clinical Neurophysiology (EEG, MEG)
  • Chapter 6. Attention Deficit Hyperactivity Disorder
  • Chapter 7. Autism Spectrum Disorders
  • Chapter 8. Delirium
  • Chapter 9. Toxins and Poisons
  • Chapter 10. Neuropsychiatry of Epilepsy
  • Chapter 11. Neuropsychiatry of Stroke
  • Chapter 12. Neuropsychiatry of Traumatic Brain Injury
  • Chapter 13. Neuropsychiatric Aspects of Hypoxic-Ischemic Brain Injury
  • Chapter 14. Neuropsychiatric Aspects of Infectious Disorders
  • Chapter 15. Neuropsychiatric Aspects of Brain Tumors
  • Chapter 16. Neuropsychiatric Aspects of Endocrine Disorders
  • Chapter 17. Neuropsychiatric Aspects of Sleep and Sleep Disorders
  • Chapter 18. Neuropsychiatric Aspects of Multiple Sclerosis and Other Demyelinating Disorders
  • Chapter 19. Neuropsychiatry of Alcohol and Other Substance Use Disorders
  • Chapter 20. Alzheimer's Disease
  • Chapter 21. Parkinson's Disease and Dementia with Lewy Bodies
  • Chapter 22. Huntington's Disease and Related Conditions
  • Chapter 23. Frontotemporal Lobar Degeneration and Related Conditions
  • Chapter 24. Neurology of Psychotic Disorders
  • Chapter 25. Neurology of Mood Disorders
  • Chapter 26. Neurology of Anxiety Disorders


    C. Alan Anderson, M.D.
    Karen E. Anderson, M.D.
    David B. Arciniegas, M.D.
    David L. Bachman, M.D.
    Nash N. Boutros, M.D.
    Lisa A. Brenner, Ph.D.
    Anil Chacko, Ph.D.
    David K. Chen, M.D.
    C. Edward Coffey, M.D.
    Kerry L. Coburn, Ph.D.
    Jeffrey L. Cummings, M.D., Sc.D.
    Richard De La Garza II, Ph.D.
    Marie A. DeWitt, M.D.
    Shreenath V. Doctor, M.D., D.D.S., Ph.D.
    Sarah E. Dreyer-Oren, B.A.
    Christopher M. Filley, M.D.
    Laura A. Flashman, Ph.D., ABPP
    James E. Galvin, M.D., M.P.H.
    David S. Geldmacher, M.D.
    Omar Ghaffar, M.D., M.Sc., FRCPC
    Ali S. Gonul, M.D.
    Tina Gurnani, M.D.
    Colin N. Haile, M.D., Ph.D.
    Robert E. Hales, M.D., M.B.A.
    Paul E. Holtzheimer III, M.D., M.S.
    Robin A. Hurley, M.D., FANPA
    Ricardo Jorge, M.D.
    Joseph S. Kass, M.D., J.D.
    Geoffrey A. Kerchner, M.D., Ph.D.
    Cynthia Y. King, M.D.
    Thomas R. Kosten, M.D.
    W. Curt LaFrance Jr., M.D., M.P.H.
    Marissa C. Natelson Love, M.D.
    Nicholas J. Milano, M.D.
    Larry D. Mitnaul Jr., M.D., M.P.H., M.S.
    Charles B. Nemeroff, M.D., Ph.D.
    Jeffrey H. Newcorn, M.D.
    Thomas F. Newton, M.D.
    Fred Ovsiew, M.D.
    Alicia S. Parker, M.D.
    Shiv S. Patel, M.D.
    Scott L. Rauch, M.D.
    Alya Reeve, M.D., M.P.H.
    Joshua J. Rodgers, M.D.
    Alasdair G. Rooney, M.B.Ch.B., M.D.
    Michael H. Rosenbloom, M.D.
    Isabelle M. Rosso, Ph.D.
    Robert M. Roth, Ph.D., ABPP
    Maria Rueda-Lara, M.D.
    Rohini D. Samudralwar, M.D.
    Melanie Selvadurai, B.H.Sc., M.B.A.
    Mohammed Sheikh, M.D.
    Samuel D. Shillcutt, Pharm.D., Ph.D.
    Jonathan M. Silver, M.D.
    Jeremy D. Slater, M.D.
    Sergio Starkstein, M.D., Ph.D.
    Dan J. Stein, M.D., Ph.D.
    Katherine Taber, Ph.D., FANPA
    Sudha Tallavajhula, M.D.
    Fadi M. Tayim, Ph.D.
    Larry E. Tune, M.D., M.A.S.
    Steven Paul Woods, Psy.D.
    Hal S. Wortzel, M.D.
    Stuart C. Yudofsky, M.D.

About the Authors

David B. Arciniegas, M.D., is Chief Medical Officer at the Center for Mental Health in Montrose, Colorado; Director of Education at the Marcus Institute for Brain Health; and Clinical Professor of Neurology and Psychiatry at the University of Colorado School of Medicine in Aurora, Colorado.

Stuart C. Yudofsky, M.D., is Distinguished Service Professor and Chairman and Drs. Beth K. and Stuart C. Yudofsky Presidential Chair of the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine; and Chairman Department of Psychiatry at Houston Methodist Hospital in Houston, Texas.

Robert E. Hales, M.D., M.B.A., is Distinguished Professor of Clinical Psychiatry at the University of California, Davis School of Medicine.

The main focus of this book is on reviewing the various neuropsychiatric disorders, which it does quite well. One chapter that is particularly helpful is on neurobiological bases of cognition, emotion, and behavior, which provides an excellent model for understanding the neurobiology of neuropsychiatric symptomatology. This is a high-quality book that provides an essential update of the fifth edition.—Eric Gausche, M.D., Doody's Book Review

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