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The Thyroid Axis and Psychiatric Illness

Edited by Russell T. Joffe, M.D., F.R.C.P.C., and Anthony J. Levitt, M.D., F.R.C.P.C.

  • ISBN 978-0-88048-364-3
  • Item #8364

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This book assembles the latest information about the relationship between thyroid state and behavior. It is intended to serve as a reference for both the basic scientist and the clinician in the field of psychiatry and the behavioral sciences.

The Thyroid Axis and Psychiatric Illness also presents the controversies, ambiguities, and unanswered questions that will be left to the future to resolve. This book not only provides information about the role of the thyroid axis in psychiatric illness, it is also designed to promote further research and understanding of this complex subject.


  • Basic Principles.

    Cerebral versus peripheral regulation and utilization of thyroid hormones. Nutrition, energy metabolism, and thyroid hormones. Interactions between thyroid hormones and other endocrine systems. The hypothalamic-pituitary-thyroid axis: clinical and theoretical.

    Clinical Principles.

    Psychiatric aspects of thyroid disease. The thyroid and depression. The thyroid and anxiety disorders. Interrelationship between the hypothalamic-pituitary-thyroid axis and alcoholism. The thyroid and eating disorders. The thyroid and schizophrenia. Index.

Drs. Joffe and Levitt's The Thyroid Axis and Psychiatric Illness will serve as a key reference work for both clinical and basic researchers with interests in the thyroid and its relevance to behavior and behavioral pathology. Among the many strengths of this volume is its depth of coverage, as evidenced by its extensive and up-to-date referencing, which is not likely to be duplicated for many years to come. Its breadth of coverage is perhaps even more impressive. In the clinical chapters, this breadth provides the context from which to judge of the robustness and specificity of thyroid-related findings heretofore widely dispersed among journal articles, chapters, and conference proceedings. In the basic science chapters, this breadth gives some indication of the many mechanisms, from the molecular to the environmental, which may be relevant to the role of the thyroid axis in maintaining behavioral homeostasis.—Mark S. Bauer, M.D., Department of Psychiatry and Human Behavior, Brown University, Department of Veterans Affairs Medical Center, Providence, Rhode Island

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