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Advances in Treatment of Bipolar Disorders

Edited by Terence A. Ketter, M.D.

  • ISBN 978-1-58562-417-1
  • Item #62417

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Clinicians searching for evidence-based quantitative assessments on which to base diagnosis and treatment of patients with bipolar disorder need look no further. Advances in Treatment of Bipolar Disorders analyzes the benefits and harms for both older and more recently developed treatments, and places these analyses in the context of the authors' many years of clinical experience. The result is a book that is both quantitatively sound and qualitatively rich, and one that will help clinicians understand the latest research and integrate it into their practices with confidence. In addition to comprehensive coverage of the most important recent advances, the book addresses advances in more specific areas, including the treatment of particular populations such as women, children, and older adults.

In addition, the book covers many critically important topics and boasts an abundance of helpful features:

  • Evidence-based quantitative assessments of benefits use numbers needed to treat for therapeutic effects and numbers needed to harm for side effects, ensuring that the quality of data supporting interventions meets a rigorous standard.
  • The book's information is based not only on controlled trials and FDA approvals but also on almost two decades of clinical research and clinical treatment experience by clinicians at Stanford University.
  • Plentiful figures and summary tables are provided to summarize the content and make it easy-to-grasp and clinician-friendly.
  • In addition to coverage of acute bipolar depression and acute manic and mixed episodes, the book provides chapters on the preventive treatment of bipolar disorder and the pharmacology of mood-stabilizing and second-generation antipsychotic medications.

Bipolar disorders are challenging and complex mental illnesses, and clinicians need all the help they can get in managing the effects of these illness on their patients' lives. Advances in Treatment of Bipolar Disorders aims to provide everything clinicians need to know to update their knowledge of this rapidly evolving field and ensure an evidence-based standard of care for this patient population.


  • Contributors
  • Preface
  • Chapter 1. Diagnosis and Treatment of Bipolar Disorder
  • Chapter 2. Treatment of Acute Bipolar Depression
  • Chapter 3. Treatment of Acute Manic and Mixed Episodes
  • Chapter 4. Bipolar Disorder Preventive Treatment
  • Chapter 5. Treatment of Pediatric Bipolar Disorder
  • Chapter 6. Treatment of Women With Bipolar Disorder
  • Chapter 7. Treatment of Older Adults With Bipolar Disorder
  • Chapter 8. Mood Stabilizers and Second-Generation Antipsychotics: Pharmacology, Drug Interactions, Adverse Effects, and Dosing
  • Index

About the Authors

Terence A. Ketter, M.D., is Professor and Chief of the Bipolar Disorders Clinic in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine in Stanford, California.

Dr. Ketter and colleagues have prepared a brilliant, scholarly summary of the never-ending rapidly evolving state of the art in the diagnosis and treatment of bipolar disorder. They have prepared a learning tool that has both scholarly appeal as well as clinically relevant pragmatic application. We owe the authors a debt of gratitude for their concise and efficient summary of the most current and clinically meaningful data in the bipolar disorders published literature.—Joseph R. Calabrese, M.D., Bipolar Disorders Research Chair, Case Western Reserve School of Medicine, Director, Mood Disorders Program, University Hospitals Case Medical Center

Given the high frequency that bipolar patients will also be taking diverse medications for similarly chronic medical disorders, the authors pragmatically discuss both direct interactions and consequences for organ function of common drugs, e.g., lithium and its renal effects in the face of concurrent ACE inhibitors. The consequences of aging on lithium-renal function parameters are similarly usefully discussed in the text. Throughout, the authors aim, and succeed, at helping the reader be a better clinician both for efficacy and safety.—Charles L. Bowden, M.D., Clinical Professor of Psychiatry and Pharmacology, Nancy U Karren Endowed Chair of Psychiatry, University of Texas Health Science Center San Antonio

Advances in Treatment of Bipolar Disorder is a timely follow up of the Handbook of Diagnosis and Treatment of Bipolar Disorder published by the same author in 2010. All chapters are led by Terry Ketter, a known expert in the field. Data from novel compounds and combination treatments not available in 2010 is included. The content of this well written book is clinically highly relevant; recommended not only for those whose main interest is bipolar disorder but also to all behavioral care providers including general psychiatrists, psychiatric nurse practitioners and primary care physicians.—Mauricio Tohen M.D., DrPH, MBA, Professor and Chairman Department of Psychiatry & Behavioral Sciences, University of New Mexico Health Sciences Center, Albuquerque New Mexico

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