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Handbook of Medicine in Psychiatry, Second Edition

Edited by Peter Manu, M.D., and Corey Karlin-Zysman, M.D.

  • ISBN 978-1-58562-496-6
  • Item #62496


Mental health clinicians who lack internal medicine experience or who do not feel comfortable addressing medical conditions in their patients will find Handbook of Medicine in Psychiatry an indispensable resource. The first evidence-based medical handbook for psychiatrists in training or practice, the book takes the reader through a series of common medical conditions, offering practical information on diagnosis and treatment of life-threatening conditions, as well as management of less serious health issues. For the second edition, the text has been thoroughly updated and restructured. The book is designed to guide clinicians to focus quickly and effectively on managing medical problems in the psychiatric setting.

The Handbook offers invaluable content and many helpful features:

  • Coverage of medical emergency management in psychiatric hospitals takes the limitations of the facility into account. For example, the chapters on caring for patients in cardiac arrest or patients in respiratory failure include practical strategies for adapting to the limited resources available in self-standing psychiatric hospitals.
  • The material on life-threatening adverse reactions to psychotropic drugs is completely up-to-date and thorough and includes guidelines for the recognition, prevention, and management of agranulocytosis, ventricular arrhythmias, pancreatitis, neuroleptic malignant syndrome, serotonin syndrome, hyperglycemic emergencies, and airway obstruction.
  • Medical deterioration in psychiatric settings is both common and critical, and the book offers cutting-edge knowledge on assessment procedures and instruments for prediction of acute medical deterioration of psychiatric inpatients.
  • Structured for easy reading and comprehension, the book’s topics are grouped into seven parts that address the essential features of clinical presentation, differential diagnosis, stratification of the risk of major complications or death, and the evidence-based approach to management, as applicable in the psychiatric setting.
  • The numerous tables, figures, and flowcharts effectively illustrate important procedures and protocols.

Completely updated and streamlined, Handbook of Medicine in Psychiatry stands alone in its completeness, its rigor, and its understanding of the environmental challenges that face the clinician delivering care to patients with serious medical and psychiatric comorbidities.


PART I: Sudden Death, Cardiac Arrest, and Respiratory Failure
Chapter 1. Sudden Death in Psychiatric Settings
Chapter 2. Cardiac Arrest
Chapter 3. Respiratory Failure
PART II: Abnormal Vital Signs
Chapter 4. Fever
Chapter 5. Hypertension
Chapter 6. Hypotension and Orthostasis
Chapter 7. Abnormal Heart Rate
PART III: Common Somatic Symptoms in Psychiatric Settings
Chapter 8. Falls and Head Trauma
Chapter 9. Obstructive Sleep Apnea
Chapter 10. Syncope
Chapter 11. Chest Pain
Chapter 12. Abdominal Pain
Chapter 13. Dysphagia
Chapter 14. Heartburn
Chapter 15. Nausea and Vomiting
Chapter 16. Bowel Habit Changes
Chapter 17. Urinary Retention, Frequency, and Incontinence
Chapter 18. Edema
Chapter 19. Headache
Chapter 20. Changes in Visual Acuity, Eye Pain, and Red Eye
PART IV: Metabolic Emergencies
Chapter 21. Hypoglycemia
Chapter 22. Severe Hyperglycemia, Diabetic Ketoacidosis, and Hyperosmolar State
Chapter 23. Hyponatremia, Hypernatremia, and Polyuric States
Chapter 24. Azotemia and Dehydration
Chapter 25. Abnormal Liver Function
Chapter 26. Hypercalcemia
Chapter 27. Hypokalemia and Hypomagnesemia
Chapter 28. Thyroid Disorders
PART V: Life-Threatening Adverse Effects of Psychotropic Drugs
Chapter 29. QTc Prolongation and Torsades de Pointes
Chapter 30. Myocarditis and Cardiomyopathy
Chapter 31. Neuroleptic Malignant Syndrome, Serotonin Syndrome, and Rhabdomyolysis
Chapter 32. Seizures
Chapter 33. Airway Obstruction
Chapter 34. Neutropenia and Agranulocytosis
Chapter 35. Pancreatitis
PART VI: Approach to the Psychiatric Patient With Acute Behavioral Disturbance
Chapter 36. Agitation and Delirium
Chapter 37. Unresponsiveness
PART VII: Medical Risk Assessments in Psychiatric Patients
Chapter 38. Risk Assessment Prior to Electroconvulsive Therapy
Chapter 39. Risk Factors for Medical Deterioration in Psychiatric Settings
Chapter 40. Integrated Care of Psychiatric Patients in Medical Settings


Jessica Abramowitz, M.D.
Herberth J. Balsells, D.O.
Sandy Balwan, M.D., FACP
Christopher Barsi, M.D.
Suresh Basnet, M.D.
Saquib Chaudhri, M.D.
Jessica Cohen, M.D.
Manjula Dhayalan, M.D.
Haskel Fleishaker, M.D.
Karen Friedman, M.D.
James Gabriels, M.D.
Mark Goldin, M.D.
Marc L. Gordon, M.D., FAAN
Harly Greenberg, M.D.
Benjamin Greenblatt, M.D., FACEP
Eugene Grudnikoff, M.D.
Farheen Hasan, M.D.
Zubair Hasan, M.D.
Chun Kit Hung, M.D.
Sean T. Hwang, M.D.
Nayla Idriss, M.D.
Patrick W. Joasil, M.D.
Semie Kang, M.D.
Imran Karim, M.D.
Corey Karlin-Zysman, M.D., FHM, FACP
Kyle C. Katona, M.D.
Saniya Kibria, M.D.
Omid Kohani, M.D., FACC
Priya Krishnasamy, M.D.
Sean LaVine, M.D.
Katherine S. Lerner, M.D.
Sam Leung, M.D.
Howard Levin, M.D.
Frederick Limson, M.D.
Peter Manu, M.D.
Amy Mastrangelo, M.D.
Joseph Mattana, M.D.
Alexandra E. McBride, M.D.
Jason Misher, M.D.
Michael Morgenstern, M.D
Sassan Naderi, M.D.
Dilip Patel, M.D.
Salonie Pereira, M.D.
Susan Philipose, M.D.
Haley S. Poland, D.O.
Mityanand Ramnarine, M.D.
Rajasree Roy, M.D.
Annabella Salvador-Kelly, M.D., FACEP
Rifka Schulman, M.D.
Hitesh H. Shah, M.D.
Sairah Sharif, M.D.
Manish Sheth, M.D.
David Y. Shih, M.D.
Matisyahu Shulman, M.D.
Liron Sinvani, M.D.
Aren Skolnick, D.O.
Lawrence G. Smith, M.D., MACP
Louis R. Spiegel, M.D.
Raymond E. Suarez, M.D.
Sara Wildstein, M.D.
Gisele Wolf-Klein, M.D.
Deyun Yang, M.D., Ph.D.
Jonathan Zilberstein, M.D.

About the Authors

Peter Manu, M.D., F.A.C.P., is Professor of Medicine and Psychiatry at Hofstra North Shore-LIJ School of Medicine; Adjunct Professor of Clinical Medicine in the Department of Psychiatry and Behavioral Sciences at Albert Einstein College of Medicine; and Director of Medical Services at The Zucker Hillside Hospital, North Shore-LIJ Department of Psychiatry, in Glen Oaks, New York.

Corey Karlin-Zysman, M.D., F.H.M., F.A.C.P., is Assistant Professor of Medicine at Hofstra North Shore-LIJ School of Medicine, and Associate Chief in the Division of Hospital Medicine at North Shore-LIJ Department of Medicine in New Hyde Park, New York.

The second edition of the Handbook of Medicine in Psychiatry is a remarkable advancement of the already highly appreciated first edition. The book is even more a valuable source of sound information for students and practitioners alike. Newly introduced chapters address highly important issues, such as sudden death in psychiatric settings and the structure of the book has been rearranged in a more pleasingly way, which supports the understanding of different aspects of common syndromes, such as metabolic emergencies. Overall, this book is a comprehensive, valuable and practical guide to physical symptoms for psychiatrists and physicians from all other disciplines.—Frank Schneider, M.D., Ph.D., Professor of Psychiatry, Psychotherapy, and Psychosomatics, RWTH Aachen University, Germany

Drs. Manu and Karlin-Zysman have made an outstanding and important contribution to the field. This is a great resource and guide for psychiatrists and other health care providers in better assessing and treating comorbid medical conditions. The Handbook is very comprehensive, accessessible, and practical. Complex diagnostic profiles are well elucidated and the integrated treatment approaches iinformative.—Douglas M. Ziedonis, M.D., MPH, Professor and Chairman, Department of Psychiatry, University of Massachusetts Medical School, UMass Memorial Health Care

The second edition of Handbook of Medicine in Psychiatry edited by Peter Manu and Corey Karlin-Sysman is in fact more a re-writing than an edition. Several new and highly skilled authors have joined the group and a useful grouping of chapters has been introduced. The handbook's obvious first priority is usability for the clinical psychiatrist. As it is further thoroughly updated and easily used because of a very specific build up of chapters this handbook will shortly be found on the shelves in every psychiatric department and clinic next to the diagnostic manuals where it can be reached by any psychiatrist, physician, medical student and nursing staff dealing with psychiatric patients. The book makes it totally clear to the reader that a psychiatrist must be a physician first, secondly a psychiatrist just as the book documents that psychiatry is truly holistic - mental illness is not only mind and brain but also soma. The pronounced excess mortality from physical diseases in mentally ill through many decades is the biggest scandal in psychiatry since the era of the backward. This book offers the practical tools to overcome this.—Povl Munk-Jørgensen, M.D., Professor, HonFRCPsych

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