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Clinical Manual of Anxiety Disorders

Edited by Dan J. Stein, M.D., Ph.D.

  • ISBN 978-1-58562-076-0
  • Item #62076

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Anxiety disorders are among the most prevalent, persistent, disabling, and costly psychiatric disorders, yet they are often underdiagnosed and undertreated. Fortunately, there have been major advances in understanding and treating these conditions in recent years; this is one of the most exciting areas in modern medicine.

This clinical manual has earned its place in the literature as one of just a few volumes that covers all of the major anxiety disorders and presents integrated contributions from both psychopharmacologists and psychotherapists—all in one compact work written for busy clinicians.

Though concepts of anxiety have long enjoyed a central position in philosophical and psychoanalytic theories, empirical research on anxiety disorders has a relatively short history. Here, 16 experts discuss advances in diagnosis, assessment (including relevant rating scales), pharmacotherapy, and psychotherapy.

This volume begins by reviewing recent important diagnostic, epidemiological, neurobiological, and treatment findings—all of which have significant implications for clinicians. Subsequent chapters cover

  • Panic disorder and agoraphobia—Laboratory studies of fear have significantly advanced our understanding of the neurocircuitry and neurochemistry of panic. Furthermore, panic disorder is now readily treated with both medications and psychotherapy.

  • Specific phobia—Viewed for many years as mild and even trivial, this common disorder is now recognized for its very real associated distress and impairment. Exposure therapy is the treatment mainstay, though pharmacotherapy should be considered particularly when there is comorbidity.

  • Social phobia (or social anxiety disorder)—In the past few years, the first FDA-approved medications for this disorder have been made available. Cognitive-behavioral therapy is also effective for the treatment of this underdiagnosed and undertreated condition.

  • Obsessive-compulsive disorder (OCD)—OCD was the first disorder where it was shown that both specific medications and cognitive-behavioral techniques resulted in normalization of activity in particular brain structures. It is now possible to provide patients with integrated treatment approaches.

  • Posttraumatic stress disorder (PTSD)—Once viewed as a normal reaction to trauma, PTSD is increasingly understood as a pathological response, characterized by specific psychobiological dysfunctions. Again, there have been exciting advances in the treatment of this disorder, with the release of the first FDA-approved agents for PTSD.

  • Generalized anxiety disorder (GAD)—For a number of years GAD was thought of as a residual disorder occasionally seen in combination with more primary conditions. Nowadays, we know that GAD is an independent condition that is prevalent, persistent, and disabling.

Busy residents and psychiatrists in active clinical practice, psychologists, primary care practitioners, and other mental health professionals will find this clinical manual—with its integrated approach of both pharmacotherapy and psychotherapy—a valuable tool in their everyday practices.


  • Contributors
  • Chapter 1. Introduction
  • Chapter 2. Panic Disorder and Agoraphobia
  • Chapter 3. Specific Phobia
  • Chapter 4. Social Phobia
  • Chapter 5. Obsessive-Compulsive Disorder
  • Chapter 6. Posttraumatic Stress Disorder and Acute Stress Disorder
  • Chapter 7. Generalized Anxiety Disorder
  • Appendix: Internet Resources
  • Index


    Richard G. Heimberg, Ph.D.
    Jonathan D. Huppert, Ph.D.
    Michael Jenike, M.D.
    Nancy Keuthen, Ph.D.
    Gustavo Kinrys, M.D.
    Eduardo Leonardo, M.D., Ph.D.
    Jane A. Luterek, M.A.
    Randall D. Marshall, M.D.
    Brian Martis, M.D.
    Mark H. Pollack, M.D.
    Barbara Rothbaum, Ph.D.
    Moira Rynn, M.D.
    Franklin R. Schneier, M.D.
    Dan J. Stein, M.D., Ph.D.
    Bavanisha Vythilingum, M.B.
    Kimberly A. Wilson, Ph.D.

About the Authors

Dan J. Stein, M.D., Ph.D., is Director of the MRC Research Unit on Anxiety and Stress Disorders in the Department of Psychiatry at the University of Stellenbosch in Cape Town, South Africa.

Dr. Stein and colleagues are to be congratulated for putting together such a helpful and user-friendly treatment manual. The chapters are well-organized and present state-of-the-art information for busy clinicians including tips for assessment, discussion of risk factors and etiology, and treatment algorithms. I recommend this manual highly.—Donald W. Black, M.D., Professor of Psychiatry, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa

Clinical Manual of Anxiety Disorders is relatively short and it is good—quite good, in fact. The editor is to be commended for assembling many of the 'big names' in anxiety disorders and inducing them to produce succinct yet comprehensive overviews following a format that provides remarkable chapter-to-chapter consistency. . . . Overall, the book gets my seal of approval. It is small enough to digest in easy bites yet large enough to be thoroughly nourishing. Its readership should extend from the greenest of residents to the most seasoned old-timers and include all clinicians (including primary care physicians) who deal with anxiety disorders. Just as I have enjoyed and appreciated reading the book in its current form, so do I look forward to future editions.—James W. Jefferson, M.D., The American Journal of Psychiatry, 2/1/2005

This manual provides a current, 'evidence-based' overview of the anxiety disorders in one brief, readable, consistent volume. . . [T]his is a useful reference book for residents, mental health workers, and practicing psychiatrists who want an overview of the anxiety disorder spectrum from the standpoint of the clinical evidence and treatment options.—Journal of Clinical Psychiatry, 2/1/2005

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