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Nicotine in Psychiatry

Psychopathology and Emerging Therapeutics

Edited by Melissa P. Piasecki, M.D., and Paul Newhouse, M.D.

  • ISBN 978-0-88048-797-9
  • Item #8797

Description

Today, 25% of Americans smoke and 50% of smokers die from tobacco-related illnesses. Meanwhile, little attention has been given to implementing cessation therapies for our patients who smoke.

Nicotine in Psychiatry: Psychopathology and Emerging Therapeutics examines this timely subject. The book's contributors, subject matter experts in the growing field of nicotine neurobiology andclinical pharmacology, cover the latest knowledge on

  • The pharmacokinetics and pharmacodynamics of nicotine
  • The effect of nicotinic receptors on the central nervous system (CNS), the recent advances made in understanding the normal function of these receptors, and how this knowledge transfers to the clinical treatment of many CNS disorders
  • Behavioral factors influencing the effects of nicotine and nicotine's addictive capacity
  • The association between smoking and specific mental disorders and the association between nicotine and mood
  • Clinical applications of nicotine as a potential therapeutic agent for a variety of disorders, such as attention deficit, Alzheimer's and Parkinson's diseases, epilepsy, inflammatory bowel disease, schizophrenia, and Tourette's syndrome
  • Nicotine replacement therapies and various smoking-cessation strategies

This book makes fascinating reading for anyone interested in the recent tobacco public policy debates, as well as clinicians and researchers looking for current information on nicotine and its clinical applications.

Contents

Contributors
Introduction to the Clinical Practice Series
Foreword
Preface
SECTION I: Background
Chapter 1. Neurobiology and Clinical Pathophysiology of Neuronal Nicotinic Acetylcholine Receptors
Chapter 2. Pharmacokinetics and Pharmacodynamics of Nicotine
Chapter 3. Behavioral Factors Influencing the Effects of Nicotine
Chapter 4. Addictive Capacity of Nicotine
SECTION II: Clinical Applications
Chapter 5. Nicotine and Major Mental Disorders
Chapter 6. Smoking, Nicotine, and Mood
Chapter 7. Nicotinic Cholinergic Systems in Alzheimer’s and Parkinson’s Diseases
Chapter 8. Smoking, Nicotine, and Movement Disorders
Chapter 9. Nicotine Effects and Attention-Deficit/Hyperactivity Disorder
Chapter 10. Nicotine Replacement Therapies and Beyond
Chapter 11. Behavioral Treatment of Cigarette Smoking and Nicotine Dependence
Afterword: Nicotine and Nicotinic Systems in Psychiatry: Past and Future
Index

About the Authors

Melissa Piasecki, M.D., is an Assistant Professor inn the Department of Psychiatry and Behavioral Sciences at the University of Nevada School of Medicine in Reno, Nevada.

Paul A. Newhouse, M.D., is the Director of the Clinical Neuroscience Research Unit and Geriatric Service and Associate Professor in the Department of Psychiatry at the University of Vermont College of Medicine in Burlington, Vermont.

I highly recommend this book for the busy clinician. In brief fashion, it explores a wide range of issues in the field of smoking and nicotine. It also offers encouragement as well as practical advice for the treatment of this much ignored but important medical condition.—Journal of Clinical Psychiatry, 6/1/2001


Nicotine and its cholinergic receptors in the brain are under increasing scrutiny as keys to the mechanism of a surprising number of psychiatric illnesses. This book offers its readers a comprehensive view of the role of nicotine in depression, Alzheimer’s and Parkinson’s disease, schizophrenia, Tourette’s syndrome, attention deficit disorder, and tobacco abuse. Many of the authors are noteworthy, as being among the first to recognize the relevance of nicotine abuse to the pathophysiology of these illnesses.—Robert Freedman, M.D., Professor, Departments of Psychiatry and Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado


The editors have assembled reviews by many of the most prestigious authorities on nicotine and nicotine addiction into a single volume. This book is comprehensive ranging from basic neurobiology to the possible therapeutic role of nicotine in human ailments. Chapters cover the potential of both behavioral and drug treatments to aid in smoking cessation. This up to the moment review will be informative to both novice and expert alike.—Alexander H. Glassman, M.D., Professor of Clinical Psychiatry, College of Physicians & Surgeons, Columbia University, New York, New York

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