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Managing the Side Effects of Psychotropic Medications

Managing the Side Effects of Psychotropic Medications

Joseph F. Goldberg, M.D., M.S., and Carrie L. Ernst, M.D.
Foreword by Stephen M. Stahl, M.D., Ph.D.
2012
532 pages
ISBN 978-1-58562-965-7
eBook Also Available In: Paperback
Item #62965



Managing the Side Effects of Psychotropic Medications provides comprehensive, pragmatic information on anticipating and countering adverse drug effects when they occur. Cowritten by a research psychopharmacologist and a consultation-liaison psychiatrist, this book fills a void in the literature, helping mental health practitioners assess the risks and benefits of specific psychotropic medications and undertake strategies for managing adverse effects.

This volume includes a wealth of information relevant to clinical psychiatrists, psychiatric residents, and psychiatric nurses, as well as medical students engaged in a psychiatry rotation. Highlights include:


  • A review of fundamental concepts from internal medicine relevant to psychopharmacology across all major organ systems affected by antidepressants, antipsychotics, mood stabilizers, stimulants, sedative-hypnotics, and other major psychotropic classes
  • Practical discussion of the strengths and weaknesses of viable antidote strategies for common adverse drug effects, including weight gain, metabolic dysregulation, sexual dysfunction, sleep disorders, skin rashes, movement disorders, and cognitive disturbances. Readers will understand the scientific rationale and evidence base behind available methods to counteract adverse drug effects
  • An entire section on vulnerable populations, including children, the medically ill, and older adults, including the special considerations in prescribing and intervening when adverse effects arise
  • Guidance for managing emergency situations, beginning with how to determine whether such a situation—e.g., allergic reaction or overdose—exists. Easy-to-use tables provide critical information needed to respond rapidly and appropriately to emergency situations including overdoses, neurotoxicities, and systemic reactions
  • A 25-question, multiple-choice self-assessment that employs a combination of case studies and straightforward questions on mechanisms of action, key symptoms, and medication selection, providing the reader with an effective way to measure learning
  • A series of appendices that distill complex information into readily-comprehensible form on vital topics including commonly reported adverse effects, common psychotropic drug interactions, resources for practitioners, and rating scales for measuring adverse drug effects.

Most valuable of all, Managing the Side Effects of Psychotropic Medications provides concise, bottom-line summary recommendations that synthesize all available empirical and anecdotal information on psychotropic medications. Mental health practitioners will appreciate its comprehensiveness and wise counsel.

Preface. Foreword. Introduction. List of abbreviations. List of drugs. Part I: General Considerations. The psychiatrist as physician. Pharmacokinetics, pharmacodynamics and pharmacogenomics. Vulnerable populations. Adverse psychiatric effects of nonpsychotropic medications. Adverse psychiatric effects of psychiatric medications. What nonmedical therapists should know about adverse drug effects. Part II: Organ Systems. Cardiovascular system. Dermatological system. Ear, nose and throat. Electrolyte abnormalities. Endocrinopathies. Gastrointestinal system. Genitourinary and renal systems. Hematological system. Musculoskeletal system. Neurological system. Ophthalmological system. Sleep disturbances. Systemic reactions. Pregnancy and the puerperium. Emergency situations. Part III: Summary Recommendations. The future. Appendix 1: self-assessment quetsions and answers. Appendix 2: resources for practitioners. References. Index.

"This is a very, very good book: both scholarly and practical. The most junior to the most experienced clinician can learn from it and refer to it often. I plan to keep it handy."—Alan J. Gelenberg, M.D., Shively/Tan Professor and Chair, Department of Psychiatry, Penn State Milton S. Hershey Medical Center, Hershey, PA


"Clinicians need to daily negotiate the often treacherous gap between the Scylla of efficacy and the Charybdis of safety. The extant literature is lopsided, focusing far more on the perhaps simpler issue of efficacy, relegating and minimising its complex sibling, safety. In this context this singular book is an invaluable and detailed map for clinicians to negotiate these complex waters; an essential desktop companion that is packed with clinically useful information."—Michael Berk, Professor of Psychiatry, Deakin University, Professorial Research Fellow, Mental Health Research Institute, Orygen Research Centre and the University of Melbourne


"Managing Side Effects of Psychotropic Medications by Joseph Goldberg and Carrie Ernst provides comprehensive, encyclopedic, coverage of this critical topic but it really is more than a volume on drug side effects; it is actually an indispensable resource for expert practice of psychopharmacology. Not only did I upgrade my own knowledge substantially by reading this book, but I also pledged to our residency training director that every MGH resident would be given a copy!"—Jerrold F. Rosenbaum M.D., Psychiatrist-in-Chief, Massachusetts General Hospital Stanley Cobb Professor of Psychiatry, Harvard Medical School, Boston, MA

Joseph F. Goldberg, M.D., M.S., is Associate Clinical Professor of Psychiatry at Mount Sinai School of Medicine in New York, New York, and Director of the Affective Disorders Research Program at Silver Hill Hospital in New Canaan, Connecticut.

Carrie L. Ernst, M.D., a consultation-liaison psychiatrist, is Assistant Professor of Psychiatry and Assistant Director of the Psychosomatic Medicine Fellowship Program at the Mount Sinai School of Medicine, New York, New York.