Recent—and exciting—discoveries of the neuropharmacology and psychopharmacology of addictive disorders make the Clinical Manual of Addiction Psychopharmacology an essential guide to our understanding of this exceptionally challenging field.

Written with a therapeutic focus as a clinical guide for the use of pharmacotherapy in patients with substance use disorders, the Clinical Manual of Addiction Psychopharmacology offers

• In-depth background discussion on each major class of drug and its treatment.
  
• Meticulously detailed reviews of the pharmacology of addictive drugs and the medications used to treat dependence on these addictive drugs.
  
• The latest work of 24 recognized experts from both the United States and abroad—all contributors to the empirical literature covered here.
  
• Nine chapters, highlighted by informative illustrations, covering all of the major classes of substances that are clinically important in relation to addiction: alcohol, opioids, sedative-hypnotics, cannabis, cocaine and psychostimulants, hallucinogens and phencyclidine, club drugs (gamma-hydroxybutyrate, ecstasy, and ketamine), inhalants, and tobacco.
  
• A discussion of psychosocial treatments combined with pharmacotherapy for alcohol, cocaine, and opioid use disorders. The goal of this approach is to optimize outcomes by understanding how patient characteristics, such as substance use disorder typology, severity, family history, and comorbid psychopathology, may interact with psychosocial and pharmacological treatment.

Each chapter covers three primary aspects of a major drug group: an overview of the clinical pharmacology of the abused substance, phenomenology or pharmacological treatment or both of the abstinence syndrome, and pharmacological treatment for relapse prevention.

For disorders in which no clear pharmacotherapy has proven effective (e.g., cocaine dependence), or for disorders in which no clear abstinence syndrome has been established (e.g., marijuana dependence), authors review the basic pharmacology of the drug and the phenomenology of withdrawal to enable clinicians to evaluate new clinical research in medications development for those disorders.

An essential guide for clinical and social work, the Clinical Manual of Addiction Psychopharmacology will find a wide audience among all prescribing clinicians, psychiatric educators and their students, and other mental health practitioners.

Alcohol. Opioids. Sedative-Hypnotics. Cannabis. Cocaine and psychostimulants. Hallucinogens and phencyclidine. Club drugs. Inhalants. Tobacco. Psychotherapy and pharmacotherapy in treatment of substance use disorders. Index.

"The Clinical Manual of Addiction Psychopharmacology fills an important need in the literature—an up-to-date volume on the pharmacological treatment of alcohol and drug abuse. This book brings pharmacotherapy into the addiction treatment setting, addressing a range of topics from the expected (alcohol, tobacco, opiates, cocaine) to the unconventional (hallucinogens, club drugs, and inhalants). The book is an excellent and timely work that should be an invaluable resource for clinicians and researchers alike."—Helen Pettinati, Ph.D., Professor, Department of Psychiatry, Director, Treatment Research Division, Addiction Treatment Research Center, University of Pennsylvania School of Medicine

"The long-overdue bridge between drug therapy and psychotherapy is developed expertly in this valuably informative handbook edited by Kranzler and Ciraulo. . . . With regard to the contribution to our knowledge and the style and format for conveying information to the reader, this text is outstanding. The reference lists for each chapter are exceptionally thorough and timely."—PsycCritiques, January 2006

"One of the best characteristics of [Clinical Manual of Addiction Psychopharmacology] is the fact that most of its chapters cover all critical clinical and basic areas for the purpose of comprehensively understanding the substances addressed. The editors have also assembled a roster of experts who are highly distinguished clinicians, educators, and investigators vis-à-vis the use and abuse of the substances covered in their assigned chapters. This group of top experts in the field of addiction adds nicely to the quality and relevance of this manual."—Journal of Clinical Psychiatry, January 2007

Henry R. Kranzler, M.D., is Professor of Psychiatry, Associate Scientific Director of the Alcohol Research Center, and Assistant Dean for Clinical Research at the University of Connecticut School of Medicine in Farmington, Connecticut.

Domenic A. Ciraulo, M.D., is Psychiatrist-in-Chief, Boston Medical Center, and Professor and Chairman, Division of Psychiatry, Boston University School of Medicine in Boston, Massachusetts.