Introduction. Developmental process. Part A: Background Information and Treatment Recommendations for Patients with HIV/AIDS. Summary of Treatment Recommendations. Coding system. General considerations. Disease Definition, Epidemiology, and Natural History. Basic facts about HIV infection, AIDS, and treatments. Associated features of neuropsychiatric and psychosocial importance. Prevalence of Comorbid psychiatric conditions. Formulation and Implementation of a Treatment Plan. Individuals at high risk for HIV infection. HIV-infected individuals. Clinical and Environmental Features Influencing Treatment. Sociodemographic variables. Clinical features. Special treatment situations. Part B: Review and Synthesis of Available Evidence. Data Regarding Prevention for Individuals at High Risk for HIV Infection. HIV-related risk assessment of behavior. HIV antibody testing. Interventions to reduce HIV risk behavior. Reducing maternal-fetal transmission. Postexposure prophylaxis. Special psychiatric populations. Data Regarding Psychiatric Treatments for Individuals with HIV Infection. Access to services. Pharmacologic treatment. Psychosocial treatment. Legal and ethical issues. Adherence to treatment. Specific syndromes. Part C: Future Research Needs. Individuals and organizations that submitted comments. References.